RETRACTED: Anti-relapse chemotherapy in liver echinococcosis
Abstract
Study objective – the effectiveness of clinical-based schemes of Albendazole anti-relapse chemotherapy. We studied the long-term results of surgical treatment of 709 patients with various forms of liver echinococcosis. Depending on the scheme of preventive treatment, the patients were divided into four groups. The fifth (control) group consisted of patients who did not receive anti-relapse chemotherapy with Albendazole. The recurrence frequency was evaluated by the survey 3–3,5 years after surgery. We found that Albendazole preventive treatment significantly reduces the relapse rate within 3–3,5 years after surgery. In the control group, relapse occurred in 42 cases (8,1%) (χ2 =10,6; р=0,0012), compared to 2 relapse cases in the study groups (1,1%). Aparasitic and antiparasitic regimes are necessary but not sufficient to prevent recurrence. The isolated relapse cases in various Albendazole preventive treatment schemes demonstrated no clear advantage of any scheme.
About the Authors
A. F. Chernousov
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, a Member of the RAS, a Honoured Scientists of the Russian Federation, the Head of the Faculty Surgery Department
Moscow
T. Y. Mukantaev
Mangistau regional hospital
Kazakhstan
Kazakhstan
Candidate of Medical Sciences, the Head of the Department of Videoendoscopic Surgery
Aktau
D. V. Vychuzhanin
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Dmitry V. Vychuzhanin, Candidate of Medical Sciences, surgeon with
6-1, Bolshaya Pirogovskaya str., Moscow, 119435
V. V. Levkin
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor of the Faculty Surgery Department
Moscow
R. M. Nurutdinov
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Candidate of Medical Sciences, surgeon with
Moscow
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